![[Video] Examination of abdominal vessels – Right renal artery](https://revistagastroenterologia.schwabepharma.com.mx/wp-content/uploads/2021/05/Vorschau_Sono_Clip80_580x325.jpg)
Bowel
Long-term safety of fecal microbiota transfer for recurrent Clostridioides difficile infection:
FMT appears safe with low risk of transmission of infections in a cohort study involving 609 cases. However, several new diagnoses were reported, which should be explored in future prospective studies.
Effect of IBD medications on COVID-19 outcomes
Combination therapy and monotherapy with thiopurines may be associated with an increased risk of severe COVID-19 as compared to TNF antibodies. There were no differences between the individual biologicals.
Anti-SARS-CoV-2 antibody responses in inflammatory bowel disease (IBD) patients treated with infliximab:
Infliximab was associated with attenuated serological responses to SARS-CoV-2 infection, that were further blunted by immunomodulators used as concomitant therapy in a large British cohort study.
Liver
Liver transplantation (LT)
The transplantation of livers from donors after circulatory death is associated with an increased risk of non-anastomotic biliary strictures. A current prospective, randomized study shows that hypothermic oxygenated machine perfusion lowers the risk of non-anastomotic biliary strictures in this constellation compared to conventional static cold storage.
Primary sclerosing cholangitis (PSC):
A recent multicenter retrospective analysis shows that magnetic resonance imaging (MRI) is superior to ultrasound for the detection of early-stage cholangiocarcinoma (CCA). Diagnosing CCA by MRI before the onset of symptoms is associated with improved outcomes.
Hepatitis C virus (HCV):
The benefit of HCV therapy in patients with advanced liver cirrhosis is controversial. A recent study shows that treatment response is associated with a reduced risk of disease progression in patients with Child-Pugh A cirrhosis, but not in patients with Child-Pugh B/C cirrhosis. In Child-Pugh B/C cirrhosis, 19% of patients displayed a MELD (Model of End-stage Liver Disease) score decrease of ≥ 2 points, but this did not lead to an improved clinical outcome.
Oesophagus Stomach Duodenum
Serology-based diagnostics of celiac disease in adults:
Results of 3 independent patient cohorts show that IgA transglutaminase titers of ≥ 10 x ULN have a strong predictive value to identify adults with intestinal changes diagnostic of celiac disease, thereby supporting a no-biopsy diagnostic approach.
Medical therapy for obesity
Once-weekly injections of the GLP-1 analogue semaglutide plus life style interventions in a phase 3 trial were associated with sustained and clinically meaningful reductions in body weight.
Microbiota-directed food intervention for undernutrition
The findings of a trial from Bangladesh suggest that MDCF-2, a prebiotic dietary supplement, improves body growth in children with acute moderate malnutrition, suggesting that manipulation of the microbiota may be linked to growth.
Pancreas
Aggressive periprocedural hydration to prevent post-ERCP-pancreatitis (PEP)
Aggressive hydration therapy in addition to rectal non-steroidal anti-inflammatory drugs (NSAID) did not reduce the PEP incidence as compared to rectal NSAID alone.
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