Endoscopic ultrasound-guided biopsies (EUS-FNB) without ROSE demonstrated high diagnostic accuracy independently on execution of ROSE in a randomized trial. When new-generation FNB needles are used, ROSE should not be routinely...
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A cohort study involving more than 1500 patients suggests that risk of significant bleeding and mortality following PEG placement was minimal in patients with uninterrupted periprocedural antithrombotic therapy.
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A phase 3 trial reports that pembrolizumab plus chemotherapy as compared to placebo plus chemotherapy resulted in a meaningful improvement of overall and progression-free survival in patients with esophageal squamous...
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Results of an European prospective registry involving more than 22.000 patients indicate that eradication therapies frequently induce adverse events which are usually mild and of limited duration. Their appearance does...
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In a current study from Israel liver transplant recipients showed a substantially inferior vaccine response to the Pfizer-BioNTech SARS-CoV-2 mRNA-based vaccine compared to immunocompetent individuals (approx. 50% positive antibody detection;...
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Bacterial infections develop in almost one-fifth of patients with acute variceal bleeding despite antibiotic prophylaxis. Respiratory infection is the most frequent, is an early event after admission, and is associated...
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In a large retrospective Japanese nationwide cohort study, the addition of bezafibrate to ursodeoxycholic acid was associated with improved prognosis. The number needed to treat to prevent 1 additional death...
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Piecemeal cold snare polypectomy of large SSL was technically equally efficacious to endoscopic mucosa resection in a historical comparison but virtually eliminated the risk of delayed bleeding and perforation.
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Tenapanor, a first-in-class minimally absorbed inhibitor of the apical Na+/H+ exchanger NHE3 improved IBS-C symptoms significantly better than placebo over 26 weeks and was well tolerated with mild diarrhea being...
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This study involving 1000 children confirms that in utero exposure to thiopurines or TNF antibodies did not affect health outcomes of children during their first 5 years of life.
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